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Abstract

The precision of ultrafast laser surgery holds great promise to multiple biomedical applications in the clinic, ranging from spine surgeries to scarred vocal fold treatments with high precision. The recent efforts in the development of miniaturized ultrafast laser surgery probes bring us a step closer to clinical translation. The spatial and thermal confinement of ultrafast lasers are the major distinguishing characteristic that enables control of very high precision ablations without damaging the out-of-focus matter. Nano- and microsurgery applications primarily rely on plasma-mediated ablation. One of the major aims in ultrafast laser micro-surgeries for clinical applications is maximizing the material removal rate (MRR), while keeping thermal damage negligible. Research group of Professor Adela Ben-Yakar has developed three generations of fiber-coupled ultrafast laser surgical probes for clinical applications in hard-to-reach areas in the body surgical probes.