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 Abstract:

Immuno-engineering is an interdisciplinary field using approaches in immunology, bioengineering and material sciences to manipulate immunity for therapeutic purposes. Much has been focused on how immune cells can be engineered for treating diseases spanning diabetes and cancer to infectious diseases. In this talk, I will first share my lab’s effort to enhance diabetic wound healing through mechano-activation of fibroblasts. This will be followed by the inhibition of cancer-associated fibroblasts to treat pancreatic cancer. Finally, I will discuss how the incorporation of stromal cells to immune organoids can create a more authentic in vitro human immunity in a dish model for studying infectious diseases.

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